BDBM238149 US9394290, ETO (etomidate)

SMILES CCOC(=O)c1cncn1C(C)c1ccccc1

InChI Key InChIKey=NPUKDXXFDDZOKR-UHFFFAOYSA-N

Data  2 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238149   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM238149(US9394290, ETO (etomidate))
Affinity DataIC50:  0.100nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM238149(US9394290, ETO (etomidate))
Affinity DataIC50:  0.5nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent