BDBM241108 US9409895, 19::US9630945, 19
SMILES Clc1cc(Cl)cc(COC(=O)N2CCC(CC2)NC(=O)CCc2c[nH]nn2)c1
InChI Key InChIKey=QUGNOBIRXQGNST-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 241108
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 3nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 4.20nMAssay Description:Inhibition of ATX (unknown origin) assessed as decrease in choline releaseMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells at -90 mV holding potential by Qpatch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...More data for this Ligand-Target Pair