BDBM241832 US9416139, 10::US9416139, 11

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(cc1)-c1ccc(c2CC3(Cc12)CCN(C)CC3)-c1ccc2nc([nH]c(=O)c2c1)[C@@H]1CC2CC2N1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=HKKWQGXOYXJODZ-XGXFDVDXSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 241832   

TargetGenome polyprotein [1973-2420](Hepatitis C virus genotype 1a (HCV))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM241832(US9416139, 10 | US9416139, 11)
Affinity DataEC50:  1.27nMAssay Description:The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM241832(US9416139, 10 | US9416139, 11)
Affinity DataEC50:  0.0320nMAssay Description:The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM241832(US9416139, 10 | US9416139, 11)
Affinity DataEC50:  0.438nMAssay Description:The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1973-2420](Hepatitis C virus genotype 1a (HCV))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM241832(US9416139, 10 | US9416139, 11)
Affinity DataEC50:  0.0680nMAssay Description:The Huh-7 cells transfected with HCV replicons system were seeded into 96-well plates (8,000 cells in 125 μL/well) respectively; each test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent