BDBM242741 US10030025, Compound 2::US10836768, Cpd no 2::US11731974, Compound 2::US9422299, 2::US9987274, Compound 2

SMILES CCc1nsc(n1)-c1nnc2[C@@H](C)N(CCn12)C(=O)c1ccc(F)cc1

InChI Key InChIKey=UOMUYZXEONWAOD-SNVBAGLBSA-N

Data  16 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 242741   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM242741(US10030025, Compound 2 | US10836768, Cpd no 2 | US...)
Affinity DataKi:  15nMAssay Description:Human NK-3: The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSubstance-P receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM242741(US10030025, Compound 2 | US10836768, Cpd no 2 | US...)
Affinity DataKi:  2.38E+4nMAssay Description:Human NK-1: The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 rece...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSubstance-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM242741(US10030025, Compound 2 | US10836768, Cpd no 2 | US...)
Affinity DataKi: >3.00E+4nMAssay Description:Human NK-2 The affinity of compounds of the invention for the NK-2 receptor was evaluated in CHO recombinant cells which express the human NK-2 recep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent