BDBM243330 US10053454, Example 74::US10196387, Example 75

SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1cc(cc2n(c3c(cc(cc3c12)-c1c(C)noc1C)C(N)=O)S(=O)(=O)C1CC1)C(F)(F)F

InChI Key InChIKey=SGAZCGBWEAGGSE-OKILXGFUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 243330   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243330(US10053454, Example 74 | US10196387, Example 75)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243330(US10053454, Example 74 | US10196387, Example 75)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243330(US10053454, Example 74 | US10196387, Example 75)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243330(US10053454, Example 74 | US10196387, Example 75)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM243330(US10053454, Example 74 | US10196387, Example 75)
Affinity DataIC50: <500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent