BDBM243457 US9427440, 11

SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3CC3(CC3c2c1)C(=O)N1CCN(CC1)CCN(C)S(=O)(=O)NC5=O

InChI Key InChIKey=ABQSGMOFOLGBCW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 243457   

TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243457(US9427440, 11)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [1027-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243457(US9427440, 11)
Affinity DataEC50:  55nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent