BDBM243460 US9427440, 10
SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3CC3(CC3c2c1)C(=O)NCCCCN(C)S(=O)(=O)NC5=O
InChI Key InChIKey=HOIQNJMKGAGGNF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 243460
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataIC50: 280nMpH: 7.5 T: 2°CAssay Description:Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt...More data for this Ligand-Target Pair
TargetGenome polyprotein [1027-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 60nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair