BDBM243476 US9427440, 24

SMILES CN1CCCCN(C)S(=O)(=O)NC(=O)c2ccc3c(C4CCCCC4)c4-c5cc(Cl)ccc5C=C(Cn4c3c2)C1=O

InChI Key InChIKey=CJTQLBDIXKIMDW-UHFFFAOYSA-N

Data  1 Kd  1 EC50  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 243476   

TargetGenome polyprotein [1027-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243476(US9427440, 24)
Affinity DataEC50:  1.45E+4nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243476(US9427440, 24)
Affinity DataKon:  0.00370M-1s-1 Koff:  4.80E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243476(US9427440, 24)
Affinity DataKd:  760nMpH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent