BDBM245232 US9428500, 26

SMILES COc1ccc(Cc2ccc(cc2)-c2ccnc3[nH]c4ccc(cc4c23)-c2ccc(cc2)N2CCN(C)CC2)c(OC)c1

InChI Key InChIKey=WBHQPXXUWKLHMV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 245232   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universita Degli Studi Di Milano—Bicocca

US Patent
LigandPNGBDBM245232(US9428500, 26)
Affinity DataIC50:  520nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universita Degli Studi Di Milano—Bicocca

US Patent
LigandPNGBDBM245232(US9428500, 26)
Affinity DataIC50:  520nMAssay Description:Inhibition of recombinant GST-tagged wild type ALK (1064 to 1427 residues) (unknown origin) expressed in Sf9 cells using TMB peptide as substrate pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universita Degli Studi Di Milano—Bicocca

US Patent
LigandPNGBDBM245232(US9428500, 26)
Affinity DataIC50:  590nMAssay Description:Inhibition of recombinant GST-tagged ALK L1196M mutant (1064 to 1427 residues) (unknown origin) expressed in Sf9 cells using TMB peptide as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Universita Degli Studi Di Milano—Bicocca

US Patent
LigandPNGBDBM245232(US9428500, 26)
Affinity DataIC50:  590nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent