BDBM24554 Pirinixic acid-based compound, 2c::ethyl 2-{[4-chloro-6-(quinolin-6-ylamino)pyrimidin-2-yl]sulfanyl}acetate

SMILES CCOC(=O)CSc1nc(Cl)cc(Nc2ccc3ncccc3c2)n1

InChI Key InChIKey=RGBSKQRTBGODPP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24554   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM24554(Pirinixic acid-based compound, 2c | ethyl 2-{[4-ch...)
Affinity DataEC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:For assays of intact cells, 5000,000 freshly isolated PMNL cells were resuspended in PGC buffer. After preincubation with the test compounds for 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed