BDBM246446 US9447114, 2

SMILES Cn1c2sc(Oc3cccc(Cl)c3)c(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O

InChI Key InChIKey=KHAGCYOTZHGFQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246446   

TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246446(US9447114, 2)
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246446(US9447114, 2)
Affinity DataIC50:  117nMpH: 7.4 T: 2°CAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent