BDBM246446 US9447114, 2
SMILES Cn1c2sc(Oc3cccc(Cl)c3)c(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O
InChI Key InChIKey=KHAGCYOTZHGFQM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 246446
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Affinity DataIC50: 117nMpH: 7.4 T: 2°CAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair