BDBM246595 Camptothecin (CPT)

SMILES CC[C@@]1(O)C(=O)OCC2=CN3Cc4cc5ccccc5nc4C3C=C12

InChI Key InChIKey=FBDOJYYTMIHHDH-OZBJMMHXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246595   

TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246595(Camptothecin (CPT))
Affinity DataIC50:  2.80E+3nMpH: 7.5Assay Description:In the preincubation assay, CPT concentrations were 50 and 100 μM, whereas various concentrations of compounds were 25, 50 and 100 μM. LdTOP1LS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase I/type IB small subunit(Leishmania donovani)
Karunya University

LigandPNGBDBM246595(Camptothecin (CPT))
Affinity DataIC50:  4.20E+3nMpH: 7.5Assay Description:In simultaneous relaxation assay, CPT concentrations were 50 and 100 μM, whereas concentration of compounds were 50, 100 and 200 μM. Relaxation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed