BDBM246872 US10053465, 11::US10065963, Compound 11::US10125150, Example 11::US10336759, # 11::US10479803, Example 11::US10519163, Example 11::US10675284, Example 11::US11084822, Example 11::US11130767, # 11::US11136326, Example 11::US11304949, Compound 11::US11324749, Comp. No. 11::US11406640, Comp. No. 11::US11596632, Comp. No. 11::US20240058343, Compound 11::US9732097, Example 11::{trans-3-(4-{[4-[(3- hydroxyazetidin-1- yl)methyl]-6- (trifluoromethyl) pyridin-2- yl]oxy}piperidin-1- yl)-1-[4-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]cydobutyl} acetonitrile
SMILES OC1CN(Cc2cc(OC3CCN(CC3)[C@H]3C[C@@](CC#N)(C3)n3cc(cn3)-c3ncnc4[nH]ccc34)nc(c2)C(F)(F)F)C1
InChI Key
Data 33 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 246872
Affinity DataIC50: <10nMAssay Description:Selective JAK1 inhibitors that can be used in combination with an immunomodulatory agent and steroid for the treatment of hematological diseases or d...More data for this Ligand-Target Pair