BDBM246881 US10053465, 20::US10065963, Compound 20::US10125150, Example 20::US10336759, # 20::US10479803, Example 20::US10519163, Example 20::US10675284, Example 20::US11084822, Example 20::US11130767, # 20::US11136326, Example 20::US11304949, Compound 20::US11324749, Comp. No. 20::US11406640, Comp. No. 20::US11596632, Comp. No. 20::US20240058343, Compound 20::{1-(cis-4-{[4-(1- hydroxy-1- methylethyl)-6- (trifluoromethyl) pyridin-2- yl]oxy}cyclohexyl)- 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]azetidin-3- yl}aceionitrile
SMILES CC(C)(O)c1cc(O[C@H]2CC[C@H](CC2)N2CC(CC#N)(C2)n2cc(cn2)-c2ncnc3[nH]ccc23)nc(c1)C(F)(F)F
InChI Key
Data 26 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 246881
Affinity DataIC50: <10nMAssay Description:Assays are carried out at room temperature in 50 mM HEPES, pH 7.4, 5 mM MgCl2, 50 mM NaCl, 5 mM DTT and CHAPS 0.04%. Reactions are initiated by the a...More data for this Ligand-Target Pair