BDBM24912 3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamino)-1,2-thiazole-4-carboxamide::isothiazole, 14b

SMILES NC(=O)c1c(SCC2CCCCC2)nsc1Nc1cccnc1

InChI Key InChIKey=NMUIYMCYQWYFCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24912   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24912(3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamin...)
Affinity DataIC50:  610nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed