BDBM24915 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-4-ylamino)-1,2-thiazole-4-carboxamide::isothiazole, 10e

SMILES NC(=O)c1c(SCc2ccc(Cl)cc2)nsc1Nc1ccncn1

InChI Key InChIKey=MZLDGXSGVBFEPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24915   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24915(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-...)
Affinity DataIC50:  47nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed