BDBM249168 US9453048, 10

SMILES CN[C@@H](C)C(=O)NC(Cc1ccc(OCc2ccc(cc2)C(=O)N[C@H]2CC(N(C2)C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(=O)N[C@@H]2CCCc3ccccc23)cc1)C(=O)C1CC=CC[C@@H]1C(=O)NC1CCCc2ccccc12

InChI Key InChIKey=MJRNRPHNOVZJQB-YSMPXDCXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249168   

TargetE3 ubiquitin-protein ligase XIAP [124-240](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249168(US9453048, 10)
Affinity DataIC50:  0.480nMT: 2°CAssay Description:Assays were performed in white, flat-bottom, 384-well ProxiPlates (Perkin Elmer). The final assay volume was 10 μL prepared from additions of Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM249168(US9453048, 10)
Affinity DataIC50:  0.130nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent