BDBM24919 3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5-[(methylcarbamoyl)amino]-1,2-thiazole-4-carboxamide::isothiazole, 5j::racemic

SMILES CNC(=O)Nc1snc(SC2CCc3cc(Cl)ccc23)c1C(N)=O

InChI Key InChIKey=DLMDRALHZSWJSF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24919   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24919(3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed