BDBM249277 US10017501, Compound 1020-18::US9458145, 1020-18

SMILES Cc1noc(C)c1-c1cc(-c2c(C)ccc3ncccc23)c2[nH]c(nc2c1)C1CC1

InChI Key InChIKey=KHQQNXFBTALTQF-UHFFFAOYSA-N

Data  3 KI  7 IC50  40 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249277   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataEC50:  55nMAssay Description:Inhibition of BRD4 in human MM1S cells assessed as reduction in MYC transcription measured after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed