BDBM249330 US10300060, Example 15-58::US10765676, Example 15-58::US9463192, 15-58::US9763943, 15-58::US9993479, 15-58

SMILES Nc1ncc(F)cc1-c1ccc(Oc2ncc(NC(=O)Nc3cc(ccc3-c3ccccc3)C(F)(F)F)cn2)cc1

InChI Key InChIKey=FVWIYWKWDMNSTL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249330   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM249330(US10300060, Example 15-58 | US10765676, Example 15...)
Affinity DataIC50:  2nMAssay Description:On the day before the assay, CellSenser TrkA-NFAT-bla CHO-K1 cells were suspended in an assay medium (Opti-MEM1 Reduced Serum Medium (Invitrogen) con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent