BDBM249418 US10537571, Compound 136::US10912774, Compound 136::US9434697, 136::US9730931, Compound 136
SMILES COc1cc(OC)c(Cl)c(NC(=O)N(Cc2cc(C)no2)c2cc(Nc3ccccc3NC(=O)C=C)ncn2)c1Cl
InChI Key InChIKey=AMYAAZXUYDZFKS-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 249418
Affinity DataIC50: <1nMAssay Description:Purified, recombinant FGFR4 was pre-incubated with 10 μM compound overnight at 4° C., or for 1 hour at room temperature. Following pre-incubatio...More data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Recombinant FGFR1 (2.5 nM), FGFR2 (1 nM), FGFR3 (5 nM), or FGFR4 (12 nM) (Invitrogen) was prepared as a mixture with substrate KKKSPGEYVNIEFG (...More data for this Ligand-Target Pair