BDBM250503 US9464103, (6'R,6aR,7r,10aS)-1,4-difluoro-6'-methyl-10a-[4-(trifluoromethyl)benzenesulfonyl]-6,6a,8,9,10,10a-hexahydrospiro[benzo[c]isochromene-7,3'-[1,5,6λ⁵]dioxaphosphinane]-6'-one
SMILES C[P@@]1(=O)OC[C@]2(CCC[C@@]3([C@H]2COc2c(F)ccc(F)c32)S(=O)(=O)c2ccc(cc2)C(F)(F)F)CO1
InChI Key InChIKey=NDJQIMURPHVFLX-DIGNGRNZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 250503
Affinity DataIC50: 397nMpH: 7.0Assay Description:To measure γ-secretase activity, membranes were incubated at 37° C. for 1 h in 50 μL of buffer containing 20 mM Hepes (pH 7.0) and 2 mM EDT...More data for this Ligand-Target Pair