BDBM251598 US9453031, 21

SMILES CC(C)(c1nc(nc2N3CCOC[C@@H]3COc12)-c1cccc2[nH]ncc12)S(C)(=O)=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 251598   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
FundacióN Centro Nacional De Investigaciones OncolóGicas Carlos Iii

US Patent
LigandPNGBDBM251598(US9453031, 21)
Affinity DataIC50:  400nMpH: 7.5 T: 2°CAssay Description:The kinase activity was measured by using the commercial ADP Hunter Plus assay available from DiscoveRx (#33-016), which is a homogeneous assay to me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
FundacióN Centro Nacional De Investigaciones OncolóGicas Carlos Iii

US Patent
LigandPNGBDBM251598(US9453031, 21)
Affinity DataIC50:  4.15E+3nMpH: 7.5 T: 2°CAssay Description:The kinase activity was measured by using the commercial ADP Hunter Plus assay available from DiscoveRx (#90-0083), which is a homogeneous assay to m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR [1360-2549](Homo sapiens (Human))
FundacióN Centro Nacional De Investigaciones OncolóGicas Carlos Iii

US Patent
LigandPNGBDBM251598(US9453031, 21)
Affinity DataIC50:  5.58E+3nMpH: 7.5 T: 2°CAssay Description:The enzymatic mTOR activity was measured using a LanthaScreen kinase activity assay (Invitrogen). The enzyme was purchased from Invitrogen (PV4754), ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent