BDBM25163 CHEMBL497332::N-methyl-N-(quinoxalin-6-ylmethyl)-5-(2,2,2-trifluoroacetyl)thiophene-2-carboxamide::thiophene derivative, 3i
SMILES CN(Cc1ccc2nccnc2c1)C(=O)c1ccc(s1)C(=O)C(F)(F)F
InChI Key InChIKey=RLNCISDDCDFAHS-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 25163
Affinity DataIC50: 580nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 670nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare
Curated by ChEMBL
Istituto Di Ricerche Di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of HDAC1 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of HDAC3 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare
Curated by ChEMBL
Istituto Di Ricerche Di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of HDAC6 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare
Curated by ChEMBL
Istituto Di Ricerche Di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 89nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair