BDBM25184 1-[5-(2,3-dihydro-1H-indol-1-ylcarbonyl)-1H-pyrrol-2-yl]-2,2,2-trifluoroethan-1-one::CHEMBL493784::pyrrole derivative, 31h
SMILES FC(F)(F)C(=O)c1ccc([nH]1)C(=O)N1CCc2ccccc12
InChI Key InChIKey=SHCFLTDJDAJUCC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 25184
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of HDAC6 purified from HEK293 cells by western blotMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Irbm-Merck Research Laboratories Rome
Curated by ChEMBL
Affinity DataIC50: 880nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair