BDBM25186 CHEMBL248486::N-(cyclohexylmethyl)-4-(2,2,2-trifluoroacetyl)benzamide::phenyl analogue, 35g

SMILES FC(F)(F)C(=O)c1ccc(cc1)C(=O)NCC1CCCCC1

InChI Key InChIKey=JJGHOMRZTGDXDD-UHFFFAOYSA-N

Data  2 IC50  4 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 25186   

TargetHistone deacetylase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM25186(CHEMBL248486 | N-(cyclohexylmethyl)-4-(2,2,2-trifl...)
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM25186(CHEMBL248486 | N-(cyclohexylmethyl)-4-(2,2,2-trifl...)
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalonyl-CoA decarboxylase, mitochondrial(Homo sapiens (Human))
Chugai Pharma Usa

Curated by ChEMBL
LigandPNGBDBM25186(CHEMBL248486 | N-(cyclohexylmethyl)-4-(2,2,2-trifl...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MBP fused human MCDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM25186(CHEMBL248486 | N-(cyclohexylmethyl)-4-(2,2,2-trifl...)
Affinity DataIC50:  2.50E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM25186(CHEMBL248486 | N-(cyclohexylmethyl)-4-(2,2,2-trifl...)
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM25186(CHEMBL248486 | N-(cyclohexylmethyl)-4-(2,2,2-trifl...)
Affinity DataT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed