BDBM25382 2-({7-[(3-bromophenyl)methyl]-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl}sulfanyl)acetamide::purine-2,6-dione, 25

SMILES Cn1c2nc(SCC(N)=O)n(Cc3cccc(Br)c3)c2c(=O)[nH]c1=O

InChI Key InChIKey=HKKJJBUQMXEHOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25382   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM25382(2-({7-[(3-bromophenyl)methyl]-3-methyl-2,6-dioxo-2...)
Affinity DataIC50:  1.11E+4nMpH: 7.0 T: 2°CAssay Description:BRAF kinase activity was quantified using an ELISA-based MEK phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curve f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed