BDBM255370 US9481682, 121
SMILES Nc1nccn2c(nc(-c3ccc(cc3OC3CC3)C(=O)Nc3cc(ccn3)C(F)(F)F)c12)[C@@H]1CC[C@H]2CCC(=O)N2C1
InChI Key InChIKey=WMMNTQFZCHUZSM-MJGOQNOKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 255370
Affinity DataIC50: 0.580nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK in human PBMC assessed as reduction in cell surface CD69 expression preincubated for 1 hr followed by stimulation with goat anti-hu...More data for this Ligand-Target Pair
Affinity DataIC50: 494nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in cell surface CD69 expression preincubated for 1 hr followed by stimulation with anti-...More data for this Ligand-Target Pair
Affinity DataIC50: 309nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 717nMAssay Description:Inhibition of CSK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 263nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of FRK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 865nMAssay Description:Inhibition of LYNB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of PTK6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 946nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of SRMS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 277nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 312nMAssay Description:Inhibition of TXK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of YES1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant full length BTK (unknown origin) expressed in baculovirus infected Sf9 cells using Biotin-EQEDEPEGDYFEWLE-NH2 peptide as su...More data for this Ligand-Target Pair