BDBM255555 US9499534, 2.2

SMILES CC(C)(C)n1cc(cn1)-c1cc(Nc2nccc(n2)C(F)(F)F)cc(c1)-c1cnc(s1)[C@@]1(O)CC[C@H](C(O)=O)C(C)(C)C1

InChI Key InChIKey=UUZWBMNOQNBPBU-ONOMSOESSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255555   

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM255555(US9499534, 2.2)
Affinity DataIC50:  285nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent