BDBM255592 US9499561, 11

SMILES Cc1nc(N)ncc1-c1nc(nc2c(CN3CCN(CC3)S(C)(=O)=O)csc12)N1CCOCC1

InChI Key InChIKey=FJECYRWICXOEIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255592   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255592(US9499561, 11)
Affinity DataIC50:  28.3nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255592(US9499561, 11)
Affinity DataIC50:  13.1nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent