BDBM255603 US9499561, 26

SMILES OCC(=O)N1CCN(Cc2csc3c(nc(nc23)N2CCOCC2)-c2cccc3[nH]ncc23)CC1

InChI Key InChIKey=LKOMKEGRNAHKRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255603   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255603(US9499561, 26)
Affinity DataIC50:  41nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM255603(US9499561, 26)
Affinity DataIC50:  141nMpH: 7.5 T: 2°CAssay Description: 1. Buffer preparation: 50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS. 2. Compound was formulated in 100% DMSO in a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent