BDBM257207 US9493440, 51

SMILES C[C@H]1CN(C[C@@H](C)O1)c1cc(ncn1)-c1n[nH]c2ccc(OC3(C)CC3)cc12

InChI Key

Data  13 IC50  3 EC50

PDB links: 5 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 257207   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Stanford University

Curated by ChEMBL
LigandPNGBDBM257207(US9493440, 51)
Affinity DataEC50:  30nMAssay Description:Inhibition of mouse full-length LRRK2 G2019S mutant transfected in HEK293 cells using LRRKtide as substrate in presence of ATP by incubated for 1 hr ...More data for this Ligand-Target Pair
LigandPNGBDBM257207(US9493440, 51)
Affinity DataEC50:  23nMAssay Description:Inhibition of wild type pcDNA5FRT-TO-GFP fused - LRRK2 (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
LigandPNGBDBM257207(US9493440, 51)
Affinity DataEC50:  30nMAssay Description:Inhibition of pcDNA5FRT-TO-GFP fused - LRRK2 G2019S mutant (unknown origin) transfected in HEK293 cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair