BDBM25851 3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol::hydroxyphenyl substituted thiophene, 23

SMILES Oc1cccc(c1)-c1ccc(s1)-c1cccc(O)c1

InChI Key InChIKey=SVBBCXVMACPXGW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 25851   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  173nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  745nMAssay Description:Tritiated E2 was incubated with 17beta-HSD2, cofactor, and inhibitor. The amount of labeled E1 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  745nMAssay Description:Inhibition of human placental 17betaHSD2 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  745nMAssay Description:Inhibition of human placental 17beta-HSD2 microsomal fraction using tritiated estradiol as substrate assessed as formation of estrone by HPLC analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human placental 17betaHSD1 by radiodetection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25851(3-[5-(3-hydroxyphenyl)thiophen-2-yl]phenol | hydro...)
Affinity DataIC50:  173nMAssay Description:Inhibition of human placental 17beta-HSD1 cytosolic fraction using [2, 4, 6, 7-3H]-estrone as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed