BDBM25894 (2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2-[(5-methyl-1H-pyrrol-2-yl)formamido]butanamide::N-heterocyclic dipeptide aldehyde, 12

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)[nH]1)C(C)C)C=O

InChI Key InChIKey=KGATUYHLXBXDBX-ZFWWWQNUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25894   

TargetCalpain-2 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25894((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Ovis aries (sheep))
University of Canterbury

LigandPNGBDBM25894((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed