BDBM25902 4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid::CHEMBL35::Frusemide::Furanthril::Furosemide::Furosemide (3)::Furosemide, 4::Lasix::US10172837, Furosemide

SMILES NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl

InChI Key InChIKey=ZZUFCTLCJUWOSV-UHFFFAOYSA-N

Data  26 KI  23 IC50  1 Kd  2 EC50

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25902   

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed