BDBM259339 US9505745, 16::US9790212, Example 16

SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1csc(N(CC)[C@H]2CC[C@@H](CC2)N(C)C)c1C

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 259339   

LigandPNGBDBM259339(US9505745, 16 | US9790212, Example 16)
Affinity DataIC50: <10nMAssay Description:Protocol 1: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259339(US9505745, 16 | US9790212, Example 16)
Affinity DataIC50:  25nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259339(US9505745, 16 | US9790212, Example 16)
Affinity DataIC50: <10nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259339(US9505745, 16 | US9790212, Example 16)
Affinity DataIC50:  25nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent