BDBM259489 US9526727, 5

SMILES CC[C@@H]1C[C@@]2(Cc3ccc(cc3[C@]22N=C(N)N(C[C@H]3CCCO3)C2=O)C#N)CC[C@H]1OC

InChI Key InChIKey=YXYULMWUAULFQM-SZAJALNSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259489   

TargetBeta-secretase 1 [1-454](Homo sapiens (Human))
Vitae Pharmaceutical

US Patent
LigandPNGBDBM259489(US9526727, 5)
Affinity DataIC50:  8nMpH: 4.4Assay Description:The inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE1 activity using commercially available substrate HiLyte Fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent