BDBM259807 US9505766, CN-NH2 (6)

SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(N)=O)n(CCCO)c2ncnc(N)c12

InChI Key InChIKey=SZAXHJXUPGRTIP-NTEUORMPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259807   

TargetRibosomal protein S6 kinase alpha-3 [399-740,C436V](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259807(US9505766, CN-NH2 (6))
Affinity DataIC50:  5.00E+3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259807(US9505766, CN-NH2 (6))
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent