BDBM260559 US10098900, Compound 1::US10300066, Compound 33::US9532990, 33::US9717745, 1

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4c(F)c(F)cc(F)c4F)cc3F)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=JUXVTKDUICDETA-GFCCVEGCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 260559   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260559(US10098900, Compound 1 | US10300066, Compound 33 |...)
Affinity DataIC50:  2nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260559(US10098900, Compound 1 | US10300066, Compound 33 |...)
Affinity DataIC50:  2nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260559(US10098900, Compound 1 | US10300066, Compound 33 |...)
Affinity DataIC50:  2nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260559(US10098900, Compound 1 | US10300066, Compound 33 |...)
Affinity DataIC50:  2nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent