BDBM26110 N,3-dihydroxybenzamide::aromatic hydroxamic acid, 5a

SMILES ONC(=O)c1cccc(O)c1

InChI Key InChIKey=IRGXGFPSYHAJER-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26110   

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50:  2.80E+4nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of PHD1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26110(N,3-dihydroxybenzamide | aromatic hydroxamic acid,...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of JMJD2E pre-incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed