BDBM26113 2,4 PDCA::cid_10365::pyridine carboxylate, 6a::pyridine-2,4-dicarboxylic acid

SMILES OC(=O)c1ccnc(c1)C(O)=O

InChI Key InChIKey=MJIVRKPEXXHNJT-UHFFFAOYSA-N

Data  9 KI  62 IC50  1 Kd

PDB links: 16 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26113   

TargetAspartyl/asparaginyl beta-hydroxylase(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  20nMAssay Description:Inhibition of N-His6-tagged human AspH (315-755) expressed in Escherichia coli BL21 (DE3) using 1 uM hFX-CP as substrate mixture with 3 uM 2OG, 100 u...More data for this Ligand-Target Pair
TargetAspartyl/asparaginyl beta-hydroxylase(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of N-His6-tagged human AspH (315-755) expressed in Escherichia coli BL21 (DE3) using 1 uM hFX-CP as substrate mixture with high 200 uM 2OG...More data for this Ligand-Target Pair
TargetAspartyl/asparaginyl beta-hydroxylase(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  30nMAssay Description:Inhibition of N-His6-tagged human AspH (315-755) expressed in Escherichia coli BL21 (DE3) using 1 uM hFX-CP as substrate mixture with 3 uM 2OG, 100 u...More data for this Ligand-Target Pair
TargetAspartyl/asparaginyl beta-hydroxylase(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  20nMAssay Description:Inhibition of N-His6-tagged human AspH (315-755) expressed in Escherichia coli BL21 (DE3) using high 10 uM hFX-CP as substrate mixture with 10 uM 2OG...More data for this Ligand-Target Pair