BDBM261511 US10513499, Compound 1::US11254644, Compound 1::US9708272, 1

SMILES OC(=O)c1cccc(CSc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)c1

InChI Key InChIKey=JBDVEYSPMQRWAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261511   

Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261511(US10513499, Compound 1 | US11254644, Compound 1 | ...)
Affinity DataIC50:  50nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (3OH-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261511(US10513499, Compound 1 | US11254644, Compound 1 | ...)
Affinity DataIC50:  50nMAssay Description:The activity of compounds 1-19 and 21-23 as inhibitors of ACMSD1 was determined by measuring the conversion of 3OH-Anthranilic Acid into product (i.e...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261511(US10513499, Compound 1 | US11254644, Compound 1 | ...)
Affinity DataIC50:  50nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (30H-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-amino-3-carboxymuconate-6-semialdehyde decarboxylase(Homo sapiens (Human))
Tes Pharma

US Patent
LigandPNGBDBM261511(US10513499, Compound 1 | US11254644, Compound 1 | ...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed