BDBM261638 N-(4-(3-methyl-4-((triisopropylsilyl)ethynyl)phenyl)thiazol-2-yl)-4-((4-methylpiperazin-1-yl)methyl)benzamide::US9708279, 15

SMILES CC(C)[Si](C#Cc1ccc(cc1C)-c1csc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)n1)(C(C)C)C(C)C

InChI Key InChIKey=CDBWZTXMPQGFDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261638   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261638(N-(4-(3-methyl-4-((triisopropylsilyl)ethynyl)pheny...)
Affinity DataIC50:  600nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261638(N-(4-(3-methyl-4-((triisopropylsilyl)ethynyl)pheny...)
Affinity DataIC50:  640nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent