BDBM261650 N-(4-(3-((tert-butyldimethylsilyl)ethynyl)phenyl)thiazol-2-yl)-5-(4-(4-methylpiperazine-1-carbonyl)phenyl)furan-2-carboxamide::US9708279, 27
SMILES CN1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1nc(cs1)-c1cccc(c1)C#C[Si](C)(C)C(C)(C)C
InChI Key InChIKey=MPMLXLMOARUFPX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 261650
Affinity DataIC50: 33.1nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Affinity DataIC50: 428nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair