BDBM262973 9-[3-sulfamoyl-2-(1H-tetrazol-5-yl)- 4-(trifluoromethyl)phenyl]-3- azaspiro[5.5]undecane-3- carboxamidine::US9708336, 826

SMILES NC(=N)N1CCC2(CCC(CC2)c2ccc(c(c2-c2nnn[nH]2)S(N)(=O)=O)C(F)(F)F)CC1

InChI Key InChIKey=AXPTXASLHIWRCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262973   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262973(9-[3-sulfamoyl-2-(1H-tetrazol-5-yl)- 4-(trifluorom...)
Affinity DataIC50:  1.45nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262973(9-[3-sulfamoyl-2-(1H-tetrazol-5-yl)- 4-(trifluorom...)
Affinity DataIC50:  1.36nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262973(9-[3-sulfamoyl-2-(1H-tetrazol-5-yl)- 4-(trifluorom...)
Affinity DataIC50:  0.491nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent