BDBM263601 US10087181, Compound 107::US10285988, Compound 108::US9713612, 108

SMILES Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(-c4ccnc(C)c4)c(c3)C#N)c2cn1

InChI Key InChIKey=ACFMGFQMZGGQRW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263601   

TargetProtein Wnt-3a(Homo sapiens (Human))
Curegenix

US Patent
LigandPNGBDBM263601(US10087181, Compound 107 | US10285988, Compound 10...)
Affinity DataIC50:  8nMAssay Description:Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Curegenix

US Patent
LigandPNGBDBM263601(US10087181, Compound 107 | US10285988, Compound 10...)
Affinity DataIC50:  8nMAssay Description:Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Curegenix

US Patent
LigandPNGBDBM263601(US10087181, Compound 107 | US10285988, Compound 10...)
Affinity DataIC50:  8nMAssay Description:NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a luciferase gene driven b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent