BDBM263974 2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic acid::US10173996, Example 39::US9604961, Example 39::US9714230, 39::US9908865, Example 39
SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccccc1
InChI Key InChIKey=FPJJSKKWGRACAX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 263974
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMAssay Description:Inhibition of KDM5A/KDM5B in human ZR-75-1 cells assessed as increase in H3K4me3 level after 72 hrs by fluorometric immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2A was determined in 38-well plate format under the following reaction conditions: 2 nM ...More data for this Ligand-Target Pair