BDBM264168 (E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(2-(methoxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 12
SMILES COCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1
InChI Key InChIKey=OVKAWEPHUVGRCJ-SQMXEVSSSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 264168
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical
US Patent
Shanghai Fochon Pharmaceutical
US Patent
Affinity DataIC50: 1.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair