BDBM264491 17-(5-fluoropyridin-3-yl)-N?[(RS)-3,3,3-trifluoro-2-hydroxypropyl]oestra-1,3,5(10),16-tetraene-3-carboxamide::US9714266, 20

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(ccc34)C(=O)NCC(O)C(F)(F)F)[C@@H]1CC=C2c1cncc(F)c1

InChI Key InChIKey=CZDJVZYKNVTSJL-LFMQFWLSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264491   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM264491(17-(5-fluoropyridin-3-yl)-N?[(RS)-3,3,3-trifluoro-...)
Affinity DataIC50:  12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent