BDBM26558 3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}cyclohexane-1-thiol::thiol-aryl sulfone, 24
SMILES CC#CCOc1ccc(cc1)S(=O)(=O)C1CCCC(S)C1
InChI Key InChIKey=MWJINRBCZKGRGC-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 26558
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Vertex Pharmaceuticals
Vertex Pharmaceuticals
Affinity DataKi: 30nM ΔG°: -10.2kcal/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair